Endocrine Abstracts

Introduction: Autoimmune thyroid diseases result from a dysregulation of the immune system leading to an immune attack on the thyroid. Autoimmune thyroid diseases, which include Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), are characterised by lymphocytic infiltration of the thyroid parenchyma. The mechanisms that trigger the autoimmune attack to the thyroid are not entirely known. The aim of this study was to investigate the possible contribution of Rho/Rh...

Objective: The aim of this study was to evaluate paraoxonase-1 (PON1) activities and its association with oxidative stress status in autoimmune thyroid disease (AITD).Materials and methods: Patients with 25 Hashimoto thyroiditis (HT) and 25 Graves’ disease (GD) and 27 healthy controls were enrolled in the study. Blood samples were obtained in euthyroid period and 3 months after the initiation of medical treatment. ...

Aim: Hyperinsulinaemia is frequent finding in patients with hyperprolactinemia and has associations with thyroid volume. In this study, we evaluated the association between thrombotic markers, insulin resistance, CIMT, and thyroid volume in female patients with prolactinoma.Material and methods: 38 women with prolactinoma and 24 healthy women were included to the study. We evaluated anthropometric, biochemical, hematologic and hormonal parameters as well...

Pituitary apoplexy (PA) is a rare but life-threatening medical emergency. Common predisposing factors include closed head trauma, blood pressure alterations, history of pituitary irradiation, cardiac surgery, anticoagulation, treatment with dopamine agonists, pituitary stimulation testing, and pregnancy. Hantaviruses belonging to the Bunyaviridae family are a group of rodent- or insectivore-borne single-strand ribonucleic acid (RNA) viruses. In humans, hantaviruses can cause h...

Aim: Patients with hypoparatiroidism may admit to hospitals with different symptoms.In this report we presented 3 case of hypoparatiroidism with congestive heart failure,epilepsy and muscle pain.Case 1: 31-year-old male admitted to hospital with dyspnea on lying down and evaluation revealed pericardial and pleural effusion. The patient was hospitalized to cardiology clinic with a prediagnosis of decompansated heart failure. In echocardiography ejection f...

Aim: Thyroid hormones act both insulin agonistic and antagonistic in different organs. Studies that evaluate the relationship between insulin resistance and hypo-hyperthyroidism have conflicting results, even euthyroid status was shown to change insulin sensitivity. In this study, our aim is to investigate the association between TSH, free T4, free T3 levels and insulin resistance in euthyroid patients.Method: Euthyroid 57 males, 47...

Background: Hypokalemia is a chronic condition in primary aldosteronism (PA) and hypokalemia symptoms usually can be tolerated by the patients. Hypokalemic periodic paralysis due to primary aldosteronism is rarely reported. We reported two cases of hypokalemic paralysis due to primary aldosteronism.Case 1: A 33-year-old male admitted to the emergency service with fatigue, numbness, progressive weakness in his legs and arms for 2 months. He had a hyperten...

Background: Postoperative severe polyuria is a rare condition after adrenal pheochromocytoma resection. We presented this case due to its rarity.Case: A 50-year-old women admitted to emergency service with malaise and fatigue complaint. The patient was using triple antihypertensive combination that started 10 years ago. Her medical history included cerebrovascular event due to hypertension 5 years ago. In physical examination her BMI was 20 kg/m2</s...

Introduction: Prolactinomas are frequent in women and between 20 and 40 years but rarely seen in men especially as macroadenoma. Both in microadenomas and macroadenomes unless there is not any indication for an emergent surgery, first line treatment is always medical with dopamine agonists. In this report, we presented a patient with macroprolactinoma that disappears in a short time with dopamine agonist treatment.Case: A 20-year-old boy admitted to endo...

Introduction: Most common two causes of primary hyperaldosateronism are bilateral idiopathic hyperplasia and aldosteron secreting adenoma but unilateral adrenal hyperplasia is a rare cause. We presented a primary hyperaldosteronism case that caused by unilateral adrenal hyperplasia.Case: A 56-year-old male admitted to endocrinology policlinic with complaints of polydipsia, polyuria, fatigue and muscle wasting. He had hypertension for 4 years. In physical...